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Eintrag vom: 05.09.2013.


We investigated utilisation of the Dako PD-L1 IHC 28-8 and 22C3 pharmDx assays and the Ventana PD-L1 (SP142) assay and evaluated concordance between the 28-8 and 22C3 assays in a real-world cohort of patients tested at a single US national reference laboratory.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7513267/
 NCBI


Immunohistochemical (IHC) stain for PD-L1 as a biomarker for immunotherapy is recommended in non-small cell lung cancer (NSCLC). Under the FDA the selection of patients for pembrolizumab requires...
https://www.researchgate.net/publication/344670793_Validation_of_PD-L1_immunohistochemical_stain_using_clone_22C3_on_two_Ventana_platforms_detailed_protocols_test_performance_characteristics_and_interobserver_reliability_analyses
 RESEARCHGATE


Read independent reviews on the PD-L1 IHC 22C3 pharmDx for Autostainer Link 48 from Dako North America Inc. on SelectScience
https://www.selectscience.net/product/pd-l1-ihc-22c3-pharmdx-for-autostainer-link-48
 SELECTSCIENCE


Comment: PDL1 IHC (clone 22C3 pharmDx) is an FDA approved companion diagnostic for selecting patients with triple negative breast cancer for pembrolizumab performed on a Dako Autostainer Link 48.
https://www.pathologyoutlines.com/topic/stainsPDL1.html
 PATHOLOGYOUTLINES


Agilent setzt nach FDA-Zulassung von PD-L1 IHC 22C3 auf der Dako Omnis-Plattform auf mehr Indikationen. Wie das Bewertungsthema Wettbewerber und der nächste Impuls zusammenwirken.
https://www.it-boltwise.de/agilent-nach-fda-zulassung-von-pd-l1-ihc-22c3-bewertung-markt-impulse-und-ausblick.html
 IT-BOLTWISE


For non?small cell lung cancer (NSCLC) treatment with pembrolizumab is limited to patients with tumours expressing PD-L1 assessed by immunohistochemistry (IHC) using the PD-L1 IHC 22C3 pharmDx (Dako Inc.) companion diagnostic test on the Dako Autostainer Link 48 (ASL48) platform.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183023
 PLOS


PD-L1 IHC 22C3 pharmDx Code GE006 is a qualitative immunohistochemical assay intended for use in the detection of PD-L1 protein in FFPE NSCLC HNSCC ESCC TNBC cervical cancer and gastric or GEJ adenocarcinoma tissues using EnVision FLEX visualization system on Dako Omnis.
https://www.agilent.com/en/product/dako-omnis-solution-for-ihc-ish/pharmdx-kit-for-dako-omnis/pharmdx-kit/pd-l1-ihc-22c3-pharmdx-for-use-with-dako-omnis-894718
 AGILENT


Code-Nr. GE006 60 Tests zur Verwendung mit Dako Omnis 1. Verwendungszweck Zur In-vitro-Diagnostik. hemischer Assay der den Monoclonal Mouse Anti-PD-L1 Clone 22C3 verwendet. Dieser ist für den Nachweis von PD-L1-Protein in formalinfixiertem paraffineingebettetem (FFPE) Gewebe aus nichtkleinzelligen Lungenkarzinomen (
https://www.agilent.com/cs/library/packageinsert/public/Copy%20of%20P05051DE_04.pdf
 AGILENT



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